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Scientist I/II
Ref No.: 18-08095
Location: Ridgefield, Connecticut
Apply mathematical modeling principles to current drug development to bring insight to biological mechanism of action investigations for drug development studies.
Develop biological systems models based on literature information and in-house data.
Explore, collect, and use relevant data (e.g., in-vitro, in-vivo/ex-vivo, and clinical data) for model calibration and validation.
Analyze and interpret model results and outcomes to generate testable hypotheses that will yield a quantitative mechanistic understanding of biology and drug action, and to guide appropriate design of experiments.
Communicate new ideas, findings, research areas and opportunities to advance the field within a pharmaceutical development setting (i.e., publish peer-reviewed literature, deliver oral presentations at internal expert meetings).

Must have good understanding of theory and principles of mathematical modeling and simulation.
Familiarity with computational modeling software (e.g., Matlab/Simbiology/Simulink, C++, R etc.)
Strong preference for experience in ordinary differential equation (ODE)-based modeling using Matlab/Simbiology or in agent-based modeling (ABM) in the biological/pharmacological settings.
Excellent oral and written communication skills.
Ability to multi-task and willingness to work effectively in highly collaborative and diverse environment.