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Associate Scientist
Ref No.: 17-14109
Location: San Diego, California
Summary:
As an Associate Scientist in Company's Array Development Group, you will play an integral role in developing next generation –omic Array based assays for diverse research and applied markets.
You will work as part of a fast paced, multi-disciplinary team focused on the enhancement of current, and development of new biochemical assays and workflows to understand the presence of different -omic traits on Company's proprietary BeadArray technology

Job Responsibilities: 
  • Develop, characterize and optimize assay protocols and automated workflows
  • Recognize potential problems, understand and troubleshoot assays and associated HW and equipment
  • Conduct focused research under general direction of supervisor by planning, conducting, analyzing, interpreting, and reporting recommendations based on tested experimental results. 
  • Independently execute verification and validation testing of new Array assay workflows and assay automation software.  Complete associated paperwork in accordance with  appropriate  good documentation standard
  • Conduct experiments and analyze data to support a robust supply of key components of the Infinium Assay
  • Analyze large complex data sets with statistical methodology
  • Participate in fast paced multidisciplinary development and troubleshooting teams
  • Keep a laboratory notebook, write reports and prepare presentations
  • Become an expert in Company's BeadArray assays including, but not limited to, Infinium Genotyping, Methylation, and Copy number variation.
  • Deliver results in a fast-paced, results orientated, product development environment
  • Perform other duties as assigned.
Required Skills and Experience: 
  • MSc or BSc in Biochemistry, Molecular biology, Bioengineering or other applied Biology or Chemistry field with a minimum 7 years' working experience in an industrial R&D environment
  • Hands-on experience with development and optimization of workflow / HW for biochemical assays.
  • Practical experience with design, planning and execution of system / workflow level verification and validation
  • Practical experienced with  bio physical characterization metrology (HPLC, binding assays, FACS, surface energy, fluid dynamics  etc)
  • Proven record of troubleshooting assay processes to deliver root cause and robust fixes
  • Experienced in molecular biology methods for nucleic acid analysis and manipulation including purification, amplification, labeling, hybridization for both DNA and RNA.
  • Excellent verbal/written communication and interpersonal skills.
  • Flexible and adaptable.
  • Analytical, detail-oriented, organized, takes initiative, and self-motivated.
  • Record of process driven approach to experimental design and troubleshooting, including understanding of DOE and statistical analysis  / scripting software such as JMP and R
  • Technical understanding of SNP genotyping analysis tools a benefit
  • Excellent lab notebook and documentation skills.
Preferred Skills and Experience:
  • DNA Array experience preferred.