Ref No.: 19-11419
Location: San Diego, California
Sunrise System Inc. is currently looking for Scientist in San Diego, CA with one of our top client.
 
Job Title: Scientist
Job Id: 19-11419
Location: San Diego, CA 92121
Duration: 12 months
Position Type: Hourly contract Position (W2 only)
 
Role
  • The successful candidate will conduct hands-on laboratory work such as solubility, stability, formulation development for preclinical animal species, solid state characterization, and preliminary salt/polymorph screening to inform the risk in pharmaceutical development of small molecules.
  • Formulation development includes vehicle screening, small scale screening for amorphous solid dispersion and Nano suspensions.
  • Characterization work includes HPLC/MS, XRD, TGA, DSC, and DLS.
  • The scientist will collaborate with Discovery team in San Diego and Development team in Summit, NJ.
  • The scientist will participate in the departmental meeting and present on their work on a regular basis.
  • This is a hands-on, laboratory-based role in a highly collaborative early development environment.
Prerequisites
  • B.S., M.S., or PhD in Chemistry, Pharmaceutical Sciences, or related scientific discipline.
  • Must have experiences in the pharmaceutical industry in discovery support, and early formulation development.
  • Advanced degree preferred.
Job Description
  • Provides direct on-site formulation support to enable efficacy, PK, and toxicology studies for San Diego based discovery groups
  • Conducts drug substance physicochemical characterization of NEC's to evaluate the risk in development of small molecules
  • Develop chromatography-based methods for assaying small molecule content, related impurities, and degradation products.
  • Experiences with chiral LC method development is desired.
  • Must have experience with Waters UPLC and Empower software.
  • Conducts solubilisation enhancement studies, and supports enabled formulation development (amorphous solid dispersion, Nano formulation, lipid-based formulation) to improve exposure in the preclinical species
  • Conduct preliminary salt and polymorph screening
  • Maintain equipment, interface with equipment vendors and troubleshoot problems when they occur
  • Interface with Discovery team members to design, schedule and execute experiments.
  • Strong interpersonal, communication, collaboration and problem-solving skills.
  • Ability to document work in electronic notebooks, presentations, reports and procedures.
Contact
Chenchukala Alwar
Direct: 732-313-0243| Email: Chenchukala.A@sunrisesys.com
Or
Satya S
Direct: (732) 272.0262 | Email: Satya@sunrisesys.com