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Scientist-I
Ref No.: 13-01646
Location: SPRING HOUSE, Pennsylvania
Position Type:Contract
Start Date / End Date: 10/28/2013 to 10/27/2014
Position: Scientist
Location: Spring House PA

POSITION SUMMARY:
With supervision, accountable for the execution of cellular and molecular-based experiments for the identification and evaluation of genomic-based predictive response biomarkers for specific compounds in the Oncology pipeline. Collaborate with cross-functional groups including internal Oncology Research and Bioinformatics personnel. Assist in generating technical reports, manuscripts and present data at internal meetings. Assist with routine laboratory management issues.
ESSENTIAL FUNCTIONS:
  • Execute cellular- and molecular-based assays for the identification and validation of predictive response biomarkers.
    • PCR / RFLP analysis
    • Taqman real-time PCR / analysis
    • Western blot analysis
    • ELISA, MSD
    • RNA/DNA/miRNA isolation/ analysis
    • Cell culture
    • Cellular assays when needed
  • Analyze public and internal genomic datasets in collaboration with Bioinformatics personnel.
  • Assist in the preparation of technical reports, abstracts and manuscripts when needed
  • Present data at laboratory and departmental meetings

OTHER RESPONSIBILITIES / DETAILED DUTIES:
  • Conduct, analysis and reporting of data in accordance with requirements set forth by the department. Ensure maintenance of detailed documentation of assay development methods and performance; record experimental data and accurate and highly organized laboratory notebooks. Follow appropriate SOPs and all internal documentation requirements.
  • Represent biomarker team at therapeutic working group meetings, as required.
  • Assist with routine management of the Biomarker laboratory.

EDUCATION:
B.S. with 0-3 years experience industry experience preferred.