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Research Associate
Ref No.: 18-04144
Location: South San Francisco, California
Duties:
  • Performs research and/or development in collaboration with others for projects.
  • A focus of this position will be performing cell cultivation to identify suitable lots of primary human hepatocytes for regularly-performed cytotoxicity assays, and establishing 3-dimensional spheroids for supporting our drug discovery programs.
  • Makes detailed observations, analyzes data and interprets results.
  • Investigates creates and develops new methods and technologies for project advancement.
  • Maintains a high level of professional expertise through familiarity with scientific literature.
  • May participate in scientific conferences and contribute to scientific journals. May be responsible for identifying patentable inventions.
  • May act as principal investigator in conducting own experiments.
Skills:
Successful candidates will provide scientific and technical support for platforms, assays, and programs developed or supported by the investigative toxicology group by:
  • Working independently or under the direct supervision of a Scientist to perform or support non-GLP laboratory experiments, including model development, routine toxicity screening, and mechanism of toxicity, with minimal direct supervision.
  • Performing applicable techniques (primary cell culture, flow cytometry, gene expression analysis, cell viability, high content screening, etc.) as required.
  • Maintaining documentation related to protocol execution.
  • Writing pre-clinical protocols and contributing to final reports as appropriate.
  • Adhering to departmental SOPs to ensure study integrity and quality.
  • A high level of independent work specifically with regards to method and model development.
  • The ability to independently perform all methods and conduct all study types commonly employed by the team.
  • Presenting data at project team, department, and outside meetings as appropriate.
Education:
  • Bachelors (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required
  • Masters (MS) degree is desirable, but not required.
Technical Experience Requirements:
  • 2-3+ years of experience with hypothesis-driven research and conduct of experiments to address is required.
  • Ability to independently design and conduct research to address such questions is required.
  • Ability to analyze, integrate, and present all data in a presentation is required.
  • Must be able to present data and associated materials to project teams or at other forums
  • Experience with molecular biology techniques and next-generation sequencing is highly desired